β-Carotene Produces Sustained Remissions in Patients With Oral Leukoplakia<subtitle>Results of a Multicenter Prospective Trial</subtitle>

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Beta-carotene produces sustained remissions in patients with oral leukoplakia: results of a multicenter prospective trial.

BACKGROUND Beta-Carotene has been reported to produce regressions in patients with oral leukoplakia, a premalignant lesion. However, previous studies have all been of short duration, with clinical response as the end point. OBJECTIVE To evaluate the duration of response and the need for maintenance therapy in subjects who respond to beta-carotene. METHODS In this multicenter, double-blind, ...

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ژورنال

عنوان ژورنال: Archives of Otolaryngology–Head & Neck Surgery

سال: 1999

ISSN: 0886-4470

DOI: 10.1001/archotol.125.12.1305